In Colossians 4, the apostle Paul encourages the Colossians to continue steadfastly in prayer, and he asks for their prayers for himself, that he may proclaim the gospel of Christ effectively. He instructs the Colossians to make the most of opportunities to share the gospel with others, and he commends Tychicus and Onesimus to them as faithful workers and fellow believers. Paul also sends greetings to different individuals and churches, including Nympha and the church that meets in her house, and he closes the letter by urging the Colossians to remember his imprisonment and to greet one another with love. Overall, the chapter emphasizes the importance of prayer, evangelism, fellowship, and unity in the body of Christ.