Matthew 10 describes Jesus Christ's instructions to His disciples as they embark on their first mission to preach the Gospel. In this chapter, Jesus gives them specific guidelines for their journey, instructing them to preach to the lost sheep of Israel, to avoid bringing money or provisions, and to rely on the hospitality of those who receive them. He also warns them of the potential persecution they may face and encourages them to have faith and trust in God throughout their journey. Overall, Matthew 10 serves as a fundamental guide to followers of Christ for sharing His message of love and salvation.