In the third of a series of podcasts recorded at the RCoA's Anaesthesia 2024 conference in Glasgow Professor Malcolm Sim discusses his research into the science of metabolomics, and its role in the diagnosis and treatment of sepsis. Metabolomics sits at the end of an 'omics' chain, after genomics, transcriptomics, and proteomics. It can help 'pierce the cloud' of uncertainty around sepsis, leading to better diagnosis, treatment, and outcomes.  Malcolm talks about the future of this research area and the opportunity to tailor therapies to a person's genetic or metabolic profile. He talks about how he was drawn towards anaesthesia, and what his other love - flying - has in common with the speciality.  Further reading: EMBL-EBI | What is Metabolomics